Yazar "Morra, Giulia" için listeleme
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Computational studies of G protein-coupled receptor complexes: Structure and dynamics
Şensoy, Özge; Almeida, Jose G.; Shabbir, Javeria; Moreira, Irina S.; Morra, Giulia (Elsevier Academic Press Inc, 2017)G protein-coupled receptors (GPCRs) are ubiquitously expressed transmembrane proteins associated with a wide range of diseases such as Alzheimer's, Parkinson, schizophrenia, and also implicated in in several abnormal heart ... -
Prediction and targeting of interaction interfaces in g-rotein coupled receptor oligomers
Schiedel, Anke C.; Köse, Meryem; Barreto, Carlos; Bueschbell, Beatriz; Morra, Giulia; Şensoy, Özge; Moreira, Irina Sousa (Bentham Science Publishers Ltd, 2018)Background: Communication within a protein complex is mediated by physical interactions made among the protomers. Evidence for both the allosteric regulation present among the protomers of the protein oligomer and of the ... -
Understanding the differential selectivity of arrestins toward the phosphorylation state of the receptor
Şensoy, Özge; Moreira, Irina Sousa; Morra, Giulia (American Chemical Society, 2016)Proteins in the arrestin family exhibit a conserved structural fold that nevertheless allows for significant differences in their selectivity for G-protein coupled receptors (GPCRs) and their phosphorylation states. To ...